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SEXUAL WELLNESS
PT-141
$299
A powerful peptide for sexual dysfunction in both men and women — acting on the brain, not the vascular system.
Increases sexual desire and arousal
Works on the brain — not the vascular system
Effective for both men and women
Effects can last up to 24 hours
Prescription required — licensed provider review included with every order
Treatment Overview
PT-141 (Bremelanotide) is a melanocortin receptor agonist that works through the central nervous system to enhance sexual desire and arousal. Unlike PDE5 inhibitors (such as sildenafil or tadalafil) which only target the vascular system, PT-141 activates neural pathways in the hypothalamus responsible for sexual motivation, making it highly effective for both men and women.
Increases sexual desire and arousal
Works on the brain — not the vascular system
Effective for both men and women
Effects can last up to 24 hours
Works even without stimulation
No negative cardiac interactions
Mechanism of Action
PT-141 activates MC3R and MC4R receptors in the brain's hypothalamus, triggering the release of dopamine in regions associated with sexual desire. This creates a genuine neurological arousal response, independent of blood pressure or cardiovascular function. Effects typically begin within 45–60 minutes and can last 8–12 hours, with some users experiencing sustained benefits up to 24 hours.
The Science & Data
PT-141 (as Bremelanotide / Vyleesi) received FDA approval in 2019 for hypoactive sexual desire disorder (HSDD) in premenopausal women. Multiple clinical trials in both men and women demonstrate significant improvements in desire, satisfaction, and frequency of sexual activity. It has proven especially beneficial for patients who do not respond to traditional PDE5 inhibitors.
Medical Disclaimer: The information provided is for educational purposes only and does not constitute medical advice. Clinical results vary by individual. Always consult with a licensed healthcare provider before starting any new treatment protocol.
Ideal Candidates
Men and women experiencing low libido, hypoactive sexual desire disorder, or sexual dysfunction not adequately addressed by conventional treatments. It is especially beneficial for those who cannot use vasodilatory medications due to cardiovascular conditions or those who seek a genuine increase in desire rather than just a physical response.
Dosage & Administration
Administered as a subcutaneous injection 45–60 minutes before sexual activity. The standard dose is 1.75 mg. PT-141 should not be used more than once in 24 hours or more than 8 times per month.
Personalized Dosing Plan
Your exact dosage and protocol will be determined by your provider based on your medical history and desired outcomes.
All Supplies Included
Everything you need is shipped directly to your door, including the medication, syringes, alcohol prep pads, and a sharps container.
On-Demand Timeline
A typical progression following a single administration of PT-141.
Initial Activation
0–2 HoursFollowing administration, the peptide begins binding to melanocortin receptors in the brain. Some users may experience a slight warming sensation or mild facial flushing as the central nervous system pathways for arousal are activated.
Peak Arousal
2–4 HoursThis is typically the window of peak efficacy. Both men and women report a significant increase in spontaneous sexual desire, heightened physical sensitivity, and improved physiological responses.
Sustained Effect
12–24 HoursUnlike traditional medications that wear off quickly, PT-141 remains active in the system. The enhanced libido and responsiveness often continue strongly throughout the first full day.
Prolonged Window
Up to 72 HoursThe effects gradually taper off, but many patients report lingering benefits, increased intimacy, and enhanced sexual vitality for up to three days after a single dose.
Do I qualify?
This treatment involves receiving compounded PT-141 (Bremelanotide) therapy. The goal is to support sexual health, arousal, and libido in both men and women by acting directly on the central nervous system.
Benefits include enhanced sexual desire and arousal on an as-needed basis. Common risks include nausea (which can be significant in some patients), flushing, headache, and temporary increases in blood pressure.
This treatment is elective and not medically necessary. Patients are encouraged to notify their primary care provider before starting. Alternatives include lifestyle modifications, PDE5 inhibitors (for men), or choosing to decline treatment.
Who Is Not a Good Candidate for PT-141 Therapy?
- Under 18 years of age
- Pregnant, breastfeeding, or trying to conceive
- Uncontrolled high blood pressure (hypertension)
- Known cardiovascular disease
- History of stroke or heart attack
- Severe liver or kidney disease
- Concurrent use of medications that significantly affect blood pressure
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Privacy Policy Terms of Service
The quizzes made available on the WHOLE BODY website do not create a doctor-patient relationship between the individual completing the assessment and WHOLE BODY.
Our network of US-licensed doctors adhere to rigorous medical protocols designed for patient safety and they have established exclusionary criteria to determine if an individual does not qualify for treatment. The answers an individual provides to the WHOLE BODY quiz consequently determine if the individual is screened out of eligibility for medication. A US-licensed clinician will meet with an individual after checkout to determine if they qualify for a prescription.
Clinicians retain the decision to prescribe compounded medications to patients.
All claims and benefits on this website refer to self-reported data from customers on a treatment plan that includes compounded medications and consultations with medical professionals. Results from compounded medications found on the WHOLE BODY platform may vary and be affected by an individual's adherence to the program and their clinician's recommendations. Compounded medications are produced in FDA-regulated facilities. Although these facilities are highly regulated, the medications are not FDA-approved or evaluated for safety, efficacy, or quality. The decision to use compounded drugs is guided by the licensed provider's medical judgment, which is informed by a telehealth consultation and medical history.
We encourage all prospective users of compounded medications to speak with their provider about the specific risks and benefits that may come with the use of compounded medication. WHOLE BODY does not produce compounded medications, and individuals may receive medication that looks different than what is portrayed on the website.
Pharmacy Providers
We are partnered with multiple USA certified pharmacies to bring the best product and overall experience to our members. Our team meets regularly with pharmacies to discuss any product shortages, shipping delays, and get updated reports on their medication testing.
Results vary based on starting weight, overall health, and program adherence. Results may vary. Medication prescriptions are at the discretion of medical providers and may not be suitable for everyone. Consult a healthcare professional before using medication or starting any weight loss program.
Data, photos, claims and other information may be associated with results derived from clinical trials, studies or public information and may not be representative of WHOLE BODY member experience.
Certain materials on this website, including text, images, and other media, may be generated or enhanced using artificial intelligence technologies. No representation or warranty is made regarding the accuracy, completeness, or reliability of such content. Individuals appearing in advertisements may be actors or models.
Testimonials on the website are from WHOLE BODY patients. For patient privacy, images representing those testimonials may use models.
By accepting our Terms of Use, you additionally understand and agree that WHOLE BODY is not acting as a pharmacy, nor does WHOLE BODY control or interfere with any such services. By accepting these Terms of Use, you understand and agree that you may be entering into a relationship with a pharmacy, pharmacist, and/or pharmacy group or other such relationship with any one or more such third-party entities.
WHOLE BODY HEALTH
Your partner in longevity and healthspan extension.
Science-backed treatments delivered to your door.
Treatments
© 2026 WHOLE BODY Health. All rights reserved.
Privacy Policy Terms of Service
The quizzes made available on the WHOLE BODY website do not create a doctor-patient relationship between the individual completing the assessment and WHOLE BODY.
Our network of US-licensed doctors adhere to rigorous medical protocols designed for patient safety and they have established exclusionary criteria to determine if an individual does not qualify for treatment. The answers an individual provides to the WHOLE BODY quiz consequently determine if the individual is screened out of eligibility for medication. A US-licensed clinician will meet with an individual after checkout to determine if they qualify for a prescription.
Clinicians retain the decision to prescribe compounded medications to patients.
All claims and benefits on this website refer to self-reported data from customers on a treatment plan that includes compounded medications and consultations with medical professionals. Results from compounded medications found on the WHOLE BODY platform may vary and be affected by an individual's adherence to the program and their clinician's recommendations. Compounded medications are produced in FDA-regulated facilities. Although these facilities are highly regulated, the medications are not FDA-approved or evaluated for safety, efficacy, or quality. The decision to use compounded drugs is guided by the licensed provider's medical judgment, which is informed by a telehealth consultation and medical history.
We encourage all prospective users of compounded medications to speak with their provider about the specific risks and benefits that may come with the use of compounded medication. WHOLE BODY does not produce compounded medications, and individuals may receive medication that looks different than what is portrayed on the website.
Pharmacy Providers
We are partnered with multiple USA certified pharmacies to bring the best product and overall experience to our members. Our team meets regularly with pharmacies to discuss any product shortages, shipping delays, and get updated reports on their medication testing.
Results vary based on starting weight, overall health, and program adherence. Results may vary. Medication prescriptions are at the discretion of medical providers and may not be suitable for everyone. Consult a healthcare professional before using medication or starting any weight loss program.
Data, photos, claims and other information may be associated with results derived from clinical trials, studies or public information and may not be representative of WHOLE BODY member experience.
Certain materials on this website, including text, images, and other media, may be generated or enhanced using artificial intelligence technologies. No representation or warranty is made regarding the accuracy, completeness, or reliability of such content. Individuals appearing in advertisements may be actors or models.
Testimonials on the website are from WHOLE BODY patients. For patient privacy, images representing those testimonials may use models.
By accepting our Terms of Use, you additionally understand and agree that WHOLE BODY is not acting as a pharmacy, nor does WHOLE BODY control or interfere with any such services. By accepting these Terms of Use, you understand and agree that you may be entering into a relationship with a pharmacy, pharmacist, and/or pharmacy group or other such relationship with any one or more such third-party entities.