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$185
A mitochondria-derived peptide that resets metabolic pathways, enhances insulin sensitivity, and dramatically boosts exercise performance.
Activates AMPK for metabolic reset
Improves insulin sensitivity
Enhances aerobic and anaerobic performance
Promotes fat burning and lean mass
Prescription required — licensed provider review included with every order
MOTS-c is a remarkable mitochondrial-derived peptide known as an "exercise mimetic." It regulates metabolic functions throughout the body, promoting fatty acid oxidation, enhancing insulin sensitivity, and improving exercise capacity. By acting directly on skeletal muscle, it helps optimize cellular energy production and protects against age-related metabolic decline.
Enhanced mitochondrial function & energy
Accelerated fat loss and metabolism
Significantly improved insulin sensitivity
Increased exercise capacity and endurance
Protection against metabolic decline
Support for healthy aging and cellular resilience
MOTS-c primarily targets skeletal muscle, where it activates AMPK (AMP-activated protein kinase) — a key enzyme that acts as a master regulator of cellular energy. By activating AMPK, MOTS-c mimics the physiological effects of exercise, stimulating glucose uptake, promoting fatty acid oxidation, and encouraging mitochondrial biogenesis. This systemic metabolic optimization helps the body utilize energy more efficiently and resist metabolic stress.
Research published in Cell Metabolism and Nature Communications demonstrates that MOTS-c treatment prevents age-dependent and diet-induced insulin resistance, as well as diet-induced obesity. Studies show it significantly improves physical performance, metabolic flexibility, and helps maintain metabolic homeostasis under stress, highlighting its profound potential as a therapeutic for metabolic and age-related conditions.
Medical Disclaimer: The information provided is for educational purposes only and does not constitute medical advice. Clinical results vary by individual. Always consult with a licensed healthcare provider before starting any new treatment protocol.
Adults looking to improve metabolic health, overcome weight loss plateaus, enhance athletic endurance, or proactively protect against age-related metabolic decline. It is particularly beneficial for those seeking to optimize insulin sensitivity and cellular energy production.
Typically administered as a subcutaneous injection 1 to 3 times per week, depending on the specific protocol goals (e.g., general metabolic health vs. athletic performance enhancement). Your specific protocol and dosage will be determined by your prescribing provider.
Your dose is titrated specifically for your body and goals by your provider based on your intake assessment.
Everything you need is shipped directly to your door, including the medication, syringes, alcohol prep pads, and a sharps container.
A typical progression on longevity and metabolic protocols.
Your cells begin to optimize energy production. You may start noticing subtle improvements in daily energy levels, reduced fatigue, and a slight increase in stamina during physical activities.
Systemic changes become more apparent. Many patients report enhanced physical endurance, better workout performance, and improved metabolic flexibility as the body becomes more efficient at utilizing glucose and fatty acids.
Metabolic transformations peak. This is typically when noticeable improvements in body composition, accelerated fat loss, and optimized insulin sensitivity markers are observed.
The protocol shifts into maintenance. Your cellular resilience is heightened, metabolic markers stabilize, and you are actively protecting your long-term healthspan against age-related metabolic decline.
This treatment involves receiving compounded MOTS-c therapy. The goal is to support cellular health, cognitive function, or physical recovery depending on the specific protocol.
Benefits vary by peptide but generally support longevity, vitality, and systemic resilience. Common risks include mild pain, redness, or swelling at the injection site, and temporary fatigue.
This treatment is elective and not medically necessary. Patients are encouraged to notify their primary care provider before starting. Alternatives include lifestyle modifications or choosing to decline treatment.
Your partner in longevity and healthspan extension. Science-backed treatments delivered to your door.
© 2026 WHOLE BODY Health. All rights reserved.
Privacy Policy Terms of Service
The quizzes made available on the WHOLE BODY website do not create a doctor-patient relationship between the individual completing the assessment and WHOLE BODY.
Our network of US-licensed doctors adhere to rigorous medical protocols designed for patient safety and they have established exclusionary criteria to determine if an individual does not qualify for treatment. The answers an individual provides to the WHOLE BODY quiz consequently determine if the individual is screened out of eligibility for medication. A US-licensed clinician will meet with an individual after checkout to determine if they qualify for a prescription.
Clinicians retain the decision to prescribe compounded medications to patients.
All claims and benefits on this website refer to self-reported data from customers on a treatment plan that includes compounded medications and consultations with medical professionals. Results from compounded medications found on the WHOLE BODY platform may vary and be affected by an individual's adherence to the program and their clinician's recommendations. Compounded medications are produced in FDA-regulated facilities. Although these facilities are highly regulated, the medications are not FDA-approved or evaluated for safety, efficacy, or quality. The decision to use compounded drugs is guided by the licensed provider's medical judgment, which is informed by a telehealth consultation and medical history.
We encourage all prospective users of compounded medications to speak with their provider about the specific risks and benefits that may come with the use of compounded medication. WHOLE BODY does not produce compounded medications, and individuals may receive medication that looks different than what is portrayed on the website.
Pharmacy Providers
We are partnered with multiple USA certified pharmacies to bring the best product and overall experience to our members. Our team meets regularly with pharmacies to discuss any product shortages, shipping delays, and get updated reports on their medication testing.
Results vary based on starting weight, overall health, and program adherence. Results may vary. Medication prescriptions are at the discretion of medical providers and may not be suitable for everyone. Consult a healthcare professional before using medication or starting any weight loss program.
Data, photos, claims and other information may be associated with results derived from clinical trials, studies or public information and may not be representative of WHOLE BODY member experience.
Certain materials on this website, including text, images, and other media, may be generated or enhanced using artificial intelligence technologies. No representation or warranty is made regarding the accuracy, completeness, or reliability of such content. Individuals appearing in advertisements may be actors or models.
Testimonials on the website are from WHOLE BODY patients. For patient privacy, images representing those testimonials may use models.
By accepting our Terms of Use, you additionally understand and agree that WHOLE BODY is not acting as a pharmacy, nor does WHOLE BODY control or interfere with any such services. By accepting these Terms of Use, you understand and agree that you may be entering into a relationship with a pharmacy, pharmacist, and/or pharmacy group or other such relationship with any one or more such third-party entities.
Your partner in longevity and healthspan extension.
Science-backed treatments delivered to your door.
© 2026 WHOLE BODY Health. All rights reserved.
Privacy Policy Terms of Service
The quizzes made available on the WHOLE BODY website do not create a doctor-patient relationship between the individual completing the assessment and WHOLE BODY.
Our network of US-licensed doctors adhere to rigorous medical protocols designed for patient safety and they have established exclusionary criteria to determine if an individual does not qualify for treatment. The answers an individual provides to the WHOLE BODY quiz consequently determine if the individual is screened out of eligibility for medication. A US-licensed clinician will meet with an individual after checkout to determine if they qualify for a prescription.
Clinicians retain the decision to prescribe compounded medications to patients.
All claims and benefits on this website refer to self-reported data from customers on a treatment plan that includes compounded medications and consultations with medical professionals. Results from compounded medications found on the WHOLE BODY platform may vary and be affected by an individual's adherence to the program and their clinician's recommendations. Compounded medications are produced in FDA-regulated facilities. Although these facilities are highly regulated, the medications are not FDA-approved or evaluated for safety, efficacy, or quality. The decision to use compounded drugs is guided by the licensed provider's medical judgment, which is informed by a telehealth consultation and medical history.
We encourage all prospective users of compounded medications to speak with their provider about the specific risks and benefits that may come with the use of compounded medication. WHOLE BODY does not produce compounded medications, and individuals may receive medication that looks different than what is portrayed on the website.
Pharmacy Providers
We are partnered with multiple USA certified pharmacies to bring the best product and overall experience to our members. Our team meets regularly with pharmacies to discuss any product shortages, shipping delays, and get updated reports on their medication testing.
Results vary based on starting weight, overall health, and program adherence. Results may vary. Medication prescriptions are at the discretion of medical providers and may not be suitable for everyone. Consult a healthcare professional before using medication or starting any weight loss program.
Data, photos, claims and other information may be associated with results derived from clinical trials, studies or public information and may not be representative of WHOLE BODY member experience.
Certain materials on this website, including text, images, and other media, may be generated or enhanced using artificial intelligence technologies. No representation or warranty is made regarding the accuracy, completeness, or reliability of such content. Individuals appearing in advertisements may be actors or models.
Testimonials on the website are from WHOLE BODY patients. For patient privacy, images representing those testimonials may use models.
By accepting our Terms of Use, you additionally understand and agree that WHOLE BODY is not acting as a pharmacy, nor does WHOLE BODY control or interfere with any such services. By accepting these Terms of Use, you understand and agree that you may be entering into a relationship with a pharmacy, pharmacist, and/or pharmacy group or other such relationship with any one or more such third-party entities.